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July 2010...Mark's PSA is rising. fast. I don't know what else to say.

 

May 4, 2010...

Sorry for the lapse in an update...I was locked out of my own blog for awhile!! April was a month of back and forth...decision making and then changing plans. Mark's scan did show that the cancer has moved to the bones. And his PSA was up and down a bit in April... I think now it is at about 87. There was a fluky test that showed a drop of 7 in a week...but later testing did not repeat that result. It however did cause a pause in the plan to join the clinical trial....his psa needed to be only rising. The pause gave Mark just enough time to rethink the whole chemo with the trial drug "piggybacked." Mark is loathe to start chemo for a 3 month increased life expectancy. He is more concerned with the quality of life going down than having 3 extra months of feeling cruddy. And Mark is most confident in the work he has been doing with his diet, and feels like he is closer than ever to seeing results because of it. He is doing a little myth busting with this whole PH thing, and he is controlling his Ph through a Geerson diet (most close thing to it) and the use of Alkaline water etc.  Dr. Moon is very very adamant that Mark not do chemo, and is very confident that he can rework the vaccine (fine tune it based on current blood testing), Dr. Moon is very supportive of Mark's work on his diet. And Mark still has the utmost confidence in Dr. Moon's work  (Mark affectionately calls Dr. Moon, "Moon Doggy..." only Mark Smith would give a world famous Dr. a pet name!)  Anyway, Mark feels that if the tide is still turned against him in a few months he can try chemo, but once he starts down that pathway everything else he is doing becomes non viable.

 

 

 

March 27, 2010

Scratch Houston. Eggs are now being moved to the clinical trial basket, or chemo. Mark should know next week if he got into the trial.

March 21, 2010

I talked to Mark this morning and got an update on what has transpired since last Tuesday, which was when he got the news about the biopsy on his lymph nodes coming back positive for cancer. Since I didn't mention it before the lymph nodes in question are in his left shoulder area. There were, I believe, 3 noteworthy ones, and the surgeon removed one, and biopsied the other 2. A lot seems to have happened since then.

One, he saw a ears, nose, and throat specialist. I believe he did this to rule out any other sort of infection, which the MD confirmed he does not have. This guy suggested a PET scan and if the affected lymph nodes were confined to the neck/ shoulder area, to go in and remove them all. Don't know if that will happen or not.

Next, his regular oncologist recommended chemo, and has told Mark that the side effects should be minimal outside of the obvious chemo hair do. Mark has had a big concern with the chemo wrecking the quality of the rest his life, but with the assurance that the chemo protocol is not one of the totally devastating ones, he will likely go for it. The oncologist is quite clear on the fact that there is no hope of remission with the chemo, but it can slow down the cancer growth. The oncologist is pushing to start this ASAP. (BTW, Pish on the no chance of remission! There is always a chance, that guy needs to work on his bedside manner, it might take a miracle, but they do happen! That guy's glass is always half empty I can tell.)

Most exciting, I think was Mark's conversation with Dr. Moon. Mark had emailed him and Dr. Moon got back to him right away, and wanted Mark's blood NOW and the pathology report. Dr. Moon is coming to Houston next week and he said he wants to rework Mark's vaccine, and bring it to Houston with him. Mark is going to meet with him in Houston. We will see what comes of that. Dr. Moon knows that Mark doesn't have money to get into anything elaborate again like the treatment in Korea, but who knows, maybe Dr. Moon needs an office built in Houston. It was really nice to know that Dr. Moon has an interest in Mark, and is genuinely concerned.

Mark says with all the organic juices and aspargus concoctions he has never felt better.

Oh and I had mentioned the Ph thing. Cancer can't grow in an environment with a PH level of 8.0 or higher. While most of us around here, test at about 7.5 on a regular basis, Mark has not been able to get his past 6.5...however, he reports that finally with the insane diet, he is finally getting it to budge up. :-)

For those who are interested I think Mark is leaning towards what is known as the Gleeson diet. Famous cancer fighting diet based from a clinic in Mexico, I THINK. I know Mark will read this and correct me as we go along.

Oh and I questioned Mark about the chemo protocol. I know there are standard protocols for certain cancers that have been used for years, but I know there is a growing trend toward more tailored protocols based around personal blood analysis etc. He is going to look into that before he begins the chemical warfare (chemo).

 

Lots to think about. And as our good friend Brooke reminded me, there is always HOPE. :-)

I am super glad Mark is having a great weekend....he says he is just going to go as fast as he can (enjoying life) for as long as he can.

Have a great week!

Kelly

March 2010…

No news was good news and I apologize for not being better about keeping the site updated. I think after Korea we all just exhaled and needed to go off the grid for a while and enjoy normal or at least pay attention to other calamities life throws at us. It was a good time to enjoy being a family because we are pretty sure we have the best one ever and that includes all of you that take the time to check up on things here!

Yea, yea, so what is going on? Here it is: Mark cannot be considered to be in any form of remission. The little bugger (prostate cancer!) is up in our face again. There is not much else to it.

We are not giving up, we are just going to live with it and fight a quiet battle for as long as we can. There are some holistic paths/protocols we are following, nothing Earth shattering but along the lines of diet and Ph balance etc. Mark appreciates getting articles people come across, he will probably have a PhD equivalent eventually.

With that said…we have decided to go back to using this site to let anybody who is interested know what is going on, and to give Mark and Lindy the option of just saying, “check the blog…” when faced with the questions of, “What is going on? How is Mark? “How are you?” These are very loaded questions for both of them to be faced with as there is so much going on both physically and emotionally. They just want to be able to enjoy this time in their lives while everything is still good. Mark feels good, and we still have some optimism left! We are not throwing out any timeline, because we don’t know! Good could last for years and years…that is what we are going for…stranger things have happened!

Fact is, they cannot ignore this little evil monkey (prostate cancer!) on their back, but they can try to minimize the attention they give it for now…spending too much time belaboring the issue is time taken away that they want to enjoy “normal.” We will share any new updates good or bad, this family cannot keep a secret even if they tried!!

Random Notes: Gregg and Francie, who we met in Korea came to see us. We love those two! I hope we have a chance to do that again. We also have gotten to talk with Janine, her and Glen have been amazing supporters of Mark ever since we met them in Korea. And Greta, yet another friend from Korea…We love you!! We owe you a proper email, you have been amazing about keeping us updated.

Q & A

Q: Did South Korea help?

A. Hard to say. We definitely hoped for some longer term results. Personally, I think it was still worth it, giving it a go…There was so much to the whole savemarksmith effort that meant so much to us and Mark…we would never change that or give it up.

Love to you all…

Kelly


Some techy stuff...

 

Advanced Prostate Cancer




Metastasis is more likely to occur during advanced prostate cancer. Metastatic disease refers to prostate cancer that has left the prostate gland and its neighboring organs. Advanced prostate cancer bone metastasis and lymph node metastasis, which can be local or distant, and bone metastasis are both associated with advanced prostate cancer.

What causes Prostate Cancer Metastasis?
Metastasis occurs through a process called angiogenesis. Angiogenesis is the process by which new blood vessels are formed; malignant cells are capable of ‘hitching a ride’ into another part of the body. The malignant cells can commonly become lodged in the bones or lymph nodes. From there, the cells “take root” and start dividing uncontrollably.


Prostate Cancer Lymph Node Metastasis
The body produces a fluid called lymph which contains white blood cells and circulates through the lymphatic system. Lymph nodes are small oval or circular organs that filter this fluid. Cancerous cells that circulate through the body can become trapped in the lymph nodes. Once trapped, cancerous cells can begin their cycle of unhealthy division and result in lymph node metastasis.

There are two types of lymph node metastasis: local and distant. Local lymph node metastasis is designated by clinical stage N1. Two lymph nodes lie on either side of the bladder. Because these nodes are close to the prostate gland, metastasis is considered local. If cancerous cells begin to grow in any other lymph node, the metastasis is considered distant. Distant lymph node metastasis is denoted by clinical stage M1a.

· Mark’s is distant, as of March 2010

 

November 21,09

Well I have been home 4 weeks and It has been strange. I don't know how people in the military adjust after being gone for 6 months or more I was only  in Korea for 7 weeks but the experience and the people are with me every day. Its hard to get up and go to work. It feels like I am wasting time,how much time is the question. But the situation requires that I work so off we go.

Medically I feel fine. I am currently receiving two injections every two weeks for two months and then will go to every month until Oct of 10. I will be sending blood back to Korea at the end of November and again the end of January and than the end of April. I will get the results back a minimum of 2 weeks after I send the blood. We will know more as the blood test results come back so all we can do is wait and hope.

I have not heard much from the people in Korea but have stayed in contact with a few.

Other than that its back to life as before. Which is pretty darn good.

Mark

10-24-09

Had the final meeting with Dr. Moon.

Final analysis, He says that I have/had a very bad cancer due to the high psa, 40 and rapid growth rate. And although it has been knocked down the danger is still lurking. I will be getting treatments, from Lindy at home each week for three weeks than every two weeks for 2 months, finally once a month until the year runs out. Blood work will be done Nov 29-09, Jan 29-10, and April 29-10. My feeling is that even though we have control of the monster and won this battle there is still a war to be fought. So we will watch our diet, control toxin intake, etc.

In conclusion, the fact is no one in the states could stop the psa rise. It has been stopped and reversed where it goes from here we will see, we will take it one day at a time.

Mark

Lindy is home safe and sound. Despite the loss of 1 catfish in the pond and the acquisition of 1 small dog for Goldie, the house survived their absence. Mark is due to come home this weekend sometime...  :-)

 




Oct 19,2009
Monday morning and Lindy is taking the bus to the airport, about a 11/2 hr trip. She should arrive LAX Monday cal time 11.05 am. Samantha is going to pick her up and drive her to VC. I have 5 more treatments and I am off survivor island on Sunday the 25th. The only disconcerting thing here is the return patients, not part of my plan. All the return patients have had multiple cancers some up to 3. They stayed clear for about one year and than began seeing markers again. I am hoping that with the one years treatments I am taking home and a gluten free diet we can keep this thing in check for a long time. The one thing that is in our favor is that I have not seen any return prostate patients and he has done over 200. I may be worrying to much but the thought having to do this again is not pleasant. An IV six times a week, so far 31 and god knows how many injections. This will probably be the last note while I am in Korea as we are down to 5 days and the treatments will be the same as the last 6 weeks. They will probably draw blood on Saturday for the final blood test but we will not get the results for about a week maybe more. The PSA should be at 0 and the EGFR should be under control.
Thank you every one for all the support and the opportunity to reverse the cancer. I can hardly wait to get home and get to work on something. More lake trips and desert trips.
Thanks again Mark


Ok great news.
Meeting with Dr Moon Oct 12, 09
The results of the blood work show that the indicators for cancer in the cells show nothing, all the other indicators are also at 0. The PSA  on Sept, 9 09 was at 40 the new blood taken on Oct 4,09 was at 12.2.
So the only things that he is watching for now is the PSA, which should be at about 6 based on the extra 7 days, and the epidermal growth factor receptor. I'm not sure what this is but there is a-lot on the Internet about it so we will be reading about it tonight.
Dr. Moon said it is going smoothly and with no problems.
I'm still going to extend the stay for one week. The reason for the extra week is that I can't get stem cells once I leave. Dr Moon is also going to send me home with 6 months supply of medicine and another 6 months that I will have to pay for. We don't know the cost but should know soon.
Mark

October 10ish...Julie Blog!!!
Sorry for the long delay in blogs, but really nothing has been different in the last couple days, wake up, eat, go to the clinic, come back to the hotel. Lindy and I (Julie) showed up on Tuesday night (I hate flying).  Mark is so happy to be with Belinda finally after 4 long weeks.  Dr. Moon is very busy, he has 5 more patients than normal right now.  Apperantly the test results are in becasue today Dr. Moon said "everything very good, I talk to you Monday".   YEAH ! ! ! ! ! !  Hopefully this dream WILL come true.  Dr. Moon did say that it would be best for Mark to stay here another week, which he will.  All of the people here that are getting treatment and their caregivers/family are amazing, such a great group of people that I am sure we will keep in contact with forever and even visit someday when we leave here. Today I was typed for my blood and tomorrow I will be injected with a white blood cell enhancer and then will be harvested Tuesday.  Lets hope I am a type A+ since that is very rare and there are people here that could use it.  As for Korea, what an adventure.  Mark pretty much knows the ropes by now and has taken us on a few adventures.  The taxi ride today was insane.  The driving is crazy, they pay no attention to any lights or signs and you are not even safe on the sidewalk.  The people here at the hotel are great.  We needed help hooking up the DVD so we called downstairs and someone came up right away, he could not figure it out so he said let me call my "engineer".  No joke withing 30 seconds "ding dong".  Lindy and I are convinced that they keep him in the closet that is in the hallway.  Great service.  One word of advice if Mark says lets go to Namdaemun tell him no, you want to go underneath Namdaemun, trust me it smells much better and they have a Starbucks.  Hidden 5 star shopping.  More to come Monday our time.
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...Happy Chuseok!! Korean Thanksgiving...We went to the National Museum today, beautiful, interesting, fun...(except Mark was unimpressed with the sausage sandwich (hot dog sliced with lettuce etc on wheat roll) I TOLD him, I think that has a hotdog in it. But Mark is conditioned to think if it is on the wheat roll, it must be healthier!! I am so sad I have to leave. Francie said, well, you need to leave, you just don't want to. Yep!! Finally found the neatest book on the language...24 hour method to learn Korean...lucky me, that is exactly the time I have. I did not know (but know 100% believe) that Korean is one of the most well designed and simplest languages to learn. Ha I also learned that it is an alphabetic language, and really the only 2 unalphabetic languages int he world are Chinese and Japan. I guess I assumed since it uses symbols, the symbols were for concepts not symbols for letters, just like our abcs. duh! Also today had two Korean Police Officers stop what they were doing to walk into the middle of speeding traffic and stop a cab in the middle of a 6 lane road for confused Americans. I am sorry I just haven't seen that kind of thing happening in the US. I can recall being on the sides of freeways with hazards on and having highway patrol zip on by! Oh and the hotel brought every room a little happy Thanksgiving gift of traditional Thanksgiving Songpyeon (chewy rice cracker with sesame center.) I am celebrating my Korean Thanksgiving with wine, Songpyeon and watching Mark read :-)  I am happy he just started a new really good book  is making him laugh (because the  main character is a smart ass, like him), he can work on that until Lindy and Julie get here. Mark only had stem cells today, so everybody could start their holiday and we have decided that MArk needs to email Dr. Moon more questions because his command of written English is excellent and this help (we hope) Mark's frustration at the lack of perceived communication and understanding of what is going on. Oh and a new couple showed up today...I wish them the best, sorry I won't get to know them better, but I know this group will take good care of them. Bye Korea...Kelly

Thursday...Oct 1... Woohoo, finally figured what the date is! Rough week for a lot of patients at the clinic...still lots of positives but a lot people are having complications from their afflictions and reactions to chemo etc. A lot of patients find their stays are extended dues to many factors, like slow response to treatment, illness, complications, we are hoping that doesn't happen for Mark as it is really hard to keep his household running with no income on top of the cost that a longer stay means. But if we are here and that is what it takes for the best result, it has to be done. arghhhhhhh. Mark will positively have bloodwork done next week and he started his vaccine today (a good hefty fat syringe in the butt) so hopefully that is just one more piece in this puzzle that, even being here, we still only vaguelly comprehend :-) 

I have just 1 1/2 days left until I go home. We are going to E Mart to celebrate, j/k, that is the Korean version of Walmart and it is just something to do to pass the day. The Koreans have their big 3 day Thanksgiving type holiday starting tomorrow and the whole town is excited. I almost bought Eric a spam gift pack :-)  Everyone goes to see their family and almost no one works. I need to buy Mark some model paint because while he was sick I bought the most complicated little model fighter plane I could find. He seems a little happy about it, he insists he needs paint first, and an exacto knife to build his first plastic model in 25 years. I hope he does build it and then Lindy brings it home safe so they could give it to Ethan or something.
Kelly

Wednesday, here....Tuesday for the States... Can you tell I have lost all track of time (dates). Mark has made a full recovery from his flu! So he is back full of sarcasm and good spirits. We went to the patio bbq last night. The evening was gorgeous. The air was still and cool, the food and company was outstanding. The wine, well, I can't keep complaining about the red wine (lack of quality there of) but I want spaghetti (Jackie, hint hint) and red wine asap when I get back. Anyway there was a Phillipino duet singing (really well) top 40 hits from the late 70's and early 80's. Crystal, our favorite miracle was dancing and so was the lovely Miss Nancy (hmmmm, pretty sure she was in a wheel chair all last week) and all the rest of the girls. Such an inspiring and uplifting evening. I am going to play a little joke on ol' Smith since we have such a playful banter back and forth about website music. The song that Crystal got up and danced to first was, "I will Survive," and for a group of cancer/alzheimers/parkinson/ life  warriors, it takes on a whole new meaning. So for Mark, haha, I am changing his profile song. I am going to put the evenings and newer photos on the home page, and move the archives to a "more korea" tab. This Saturday I will be heading back, and Lindy and Julie will be arriving. Bittersweet like Jackie said. I am so grateful to have been able to been a part of this. Also, I did try to get Mark to blog last night. He says, everything is status quo, hopefully some test results will be coming up as he hits the 3 week marker. The whole flu thing shifted our focus for about 4 days. Treatment continued though all the way through. I am going to have a chance to harvest once more before I leave. Lindy can donate when she gets here, and Mark and I are praying that Julie will actually first be a match for Don, as his blood type is A+ (I believe) rarer in Asian blood?

Kelly
Saturday here, Friday in States...
Took a 12,000 won cab to get here (clinic). We ended up with a totally illiterate cab driver, who was sure he knew where to take us, but he didn't. He tried hard though, and spent a lot of time conferring with other people trying to help. Finally a young Doctor/Intern at some hospital parking lot joined in, tried to look up Goodgene clinic, no luck, then became sure he knew what we were describing...got another cab and ended up at the Mario Outlet's, lucky this new cab driver was quick on the uptake and through charades knew where we wanted to go. A cab to the clinic is usually 4,000 won, about $3.50. But we are here now! It all started because Mark is so sick (congested, sore throat, low grade fever) that we don't want the other patients exposed to him. Tomorrow is a day off (Sunday here) so we won't that problem again. We usually have business cards with maps, but I ended up with only the hotel card. Big mistake!!  Mark is snoring away now, getting his normal cancer meds and a hydration IV today, with a side of antibiotics. Probably be here until maybe 2:30, since we got a late start. He definately feels better today though. Says so himself.

Lindy, in your spare time you could practice some phrases...You really need "Thank you," it is pronounced "kaum-sa-haum-nee-da, because everyone is so nice.
To new patients coming over, bring soup, feminine hygeine products (if necessary)(they are stuck in  about the 60's with that if you get my drift), small dvd player to watch dvd's if you bring them (there is a difference in the US vs Korean discs) you can buy the US player here but nothing is cheaper. Also, if the caregiver and or patient has a special preference in alcohlic beverages, buy at duty free on the way over: alcohol (one bottle allowed from duty free), it tends to very expensive here, especially wine (ie $15.00 for Yellowtail). A bottle of Absolute is $30.00 at Homeplus (Korean Target). Oh yea, bring hand sanitizer for travel and to use here...Mark is pretty sick right now and I can't help but wonder if a little more attention to the presence of germs in this huge city might have helped! Quite a few people do walk around with the  face masks, I can't decide if it because they are sick or they are afraid to get sick, probably both. I know I am ready to stick one on Mark!!



Friday?
We are staying late at the clinic today, so no skype calls, unless they are 10:00 ish :(
Lindy gets to come over a few days sooner, she is bursting with happiness and Mark is too.
Mark is battling a very bad chest cold, he gets extra goodies in his IV to try to help kick it. He is going to be stuck between the clinic and the hotel room for the next few days until that is taken care of. Lindy and Julie should bring more hand sanitizer over...and remember to tell Smith to wash his hands like 5,000 times a day!

I got harvested for my whiteblood stem cells today, it wasn't a bad experience, just weird to see the machine taking your blood whirling it around and returning it to you. I think the more they have to do it the more unpleasent it gets or it is more unpleasent t for the patients,  cause a lot of the patients are not enjoying it at all :(

Couple things I meant to add about the culture/country...NO TIPPING!! it is rude! I love it, no stress, it just cost what it cost. Also, room service costs maybe a few dollars extra rather than a billion. Since Mark was sick last night I went to get him a sandwich and they insisted on bringing it up. I was trying to just get it "to go" because I was afraid of the cost, but the language barrier made it impossible. (the language thing sometimes ends up costing a lot...ha...like we like to take the grey cabs, cause they are less fancy, thus less expensive then the black cabs...but they always want to give you the black ones! oh well. Anyway, the room service sandwich was only like 3,000 won more, like $2.50. phew.

Sodas are 8 oz. instead of 12, much nicer, actually...Red Bull size cans are standard. Granite is everywhere, evidently it is not an expensive thing!...

thats about it for now..I need to try to get word out to the family that we won't be calling until later. Can't wait for Mark to feel better.

-kelly

9/23 Wednesday in Korea

The people work harder than even Amercians, 6 day work week. EVERYBODY shops on Saturday. Everything is built vertical, so while they are the one of the top 3 most densely populated cities in the world, sometimes you can be amazed that there is so much greenery and undeveloped land outside of the city…

The city is CLEAN, I have seen 3 pieces of trash on the streets in general…Smells very city like at times, sometimes it all, yumfood smells then BAM sewery. Coffee is huge here. There are coffee places , like 3 on a block. Everybody carries designer bags, probably cause knocks offs abound?? Ha and all the logos or sayings on the tshirts are American/in English. And they seem to like the white Sox as a bball team, anyone know why???

Mark’s crew of patients and family, like Jackie said are great…we went on the Folk Village adventure today. Mark and I skipped the guided English tour and I followed Mark around as he tried (and succeeded) at figuring out the early Korean architectural HVAC systems…

More later, tomorrow we go to the clinic for Mark’s treatment. ..Jackie--the dad says he misses you cause I argue too much with him. Whatever!!

Kelly

PS I wrote this cause Mark is reading an actual book. And he likes it. It is a strange thing. He reads a lot. He was trying to explain to Crystal the type of book he likes as really good lies. We laughed and told him that some people just call that fiction!

PSS The gnomes are having fun. Mark hates them. So while he was on his IV, reading, I walked up and put 4 travel gnomes behind him, all the wives got up and started taking pictures. He looked up all surprised, figured out what was going on, and turned red. He asked his friend, Tommy, why he hadn’t told what was going on. Tommy said he hadn’t seen me…sorry. His other friend, Glen, (6’ 3” tall with a Texas oil rig accent) says, “well, I saw her, but I was just afraid.”

PSSS When Mark trys to imitate Glen’s accent, he sounds like Forest Gump

PSSSS Mark keeps noticing the crosses outside the hotel window…they are all done in red lights on top of the buildings here. He says God is ganging up on him. Maybe cause Lindy started going to church???


Week of 9/15...missing Jackie, waiting for Kelly so I can tell the tale of some Korean Shenaigans!! Otherwise, here is some more techy stuff (in Mark-ese/construction101)

Well things are along well but time is moving slowly. We now have 10 patients, so the clinic is full. I finally got to have a private meeting with Dr Moon and Greta,Greta is the wife of another patient, but we like to have two sets of ears on these things. We asked when we would get some information on whether we were winning or loosing this battle. I asked if a PSA test would give us an indication and was given a briefing on what the battle plan is.
Hello All,
I am so sorry it took me so long to get the previous blog up. I had a ton of trouble with Mark's computer for no apparent reason. We are at the clinic now. Mark is having me look up what is in his drips...
anosolANOSOL
INJ.
8.5% Amino acid Formulation for Parenteral Nutrition
Composition :
1000ml contains
8 kinds of essential amino acids ----------------- 41.9g
6 kinds of non-essential amino acids ----------- 42.9g
4 kinds of electrolytes -----------------------------95Eq/L
Characteristic : It improves nitrogen balances by promoting initial protein synthesis and minimizes crisis of hyperammonaemia.
Indications : Hypoproteinemia, lack appetite and preoperative & postoperative state
Dosage and Administration :
The maximum dose for adults is 1~1.5g/kg/day.
Solution should be infused slowly by I.V.
Expiry : 3 years How supplied : 250ml, 500ml
:
(this follows his stem cell drip, remember nothing to do with babies, they are harvested from adults...like a blood donation, part of related to whiteblood cells)

Mark misses Lindy and their rituals like cookies and coffee in bed every morning, waking up to his Avocado trees, feeding his turtles, battling the algae in the pond. He doesn't have a lot to do here. So it is nice we have oppertunity later in the day to get out and about in the city. He has mastered the subways, and now we are all casual, not clinging to the handholds looking confused!!

I find out today if I get harvested (donate stem cells). Dr Moon looks at your blood and determines if you a match, and then a good match. Jackie was definately a perfect donor, healthy and young!! She did complain at all when she got harvested and listening to all the patients getting harvested, it is not pleasent. Trooper Jackie!! My cells might not be good because I am 40 ( that is the cutoff age for donors) and my having chemo changes cell structure, so it is a maybe.

haha as soon as I finished typing that, the nurse came at me for my stomache shot to drive the whiteblood cell count in me up. I passed!! I was curious as too what the shot was, had to be something that would drive up whiteblood count. Only answer would be a low grade infection or something else your body doesn't like, to alert the fighters to reproduce.

The science Dr. Moon uses makes so much sense, and is so complimentary to your body systems it seems, just makes more sense.

Crystal is doing phenomenal, by the way. She is beautiful, upbeat, walking around and has  friend here now.

Mark is eagerly waiting for results of a psa test. All the stuff Dr. Moon hd been explaining, it seems is now at a turning point. Where Dr. Moon was driving his PSA, to give the whiteblood stem cells a good clear target to fight, he now expects a turn where the whiteblood cells begin to destroy the cancer.


First impressions etc.

Okay, so Mark says there are lots of Americans here. He’s wrong haha, we are an anomaly so everybody looks at you. I like it, people do double takes, and some are helpful and others….you can just see the surprise. The street lights run sideways, the subways are complicated for newbie’s. People like to watch you try to figure out the routes and then somebody always tries to help, that is the ones that don’t just want to look at you cause you are with a little cluster of Americans!!
Here goes.
With prostate cancer the psa measures the antigens as the marker. In this case when I came the PSA number was 23 when 4 and under is good. But more important is the speed at which it is  growing. Doubling in 6 months is considered rapid. Mine was doubling in 30 days.
The antigen that is measured with a PSA test is a low grade antigen and so the immune system does not recognize it as a problem so they don't go after these cell and they are free to grow.
They then go in and look at the cell to determine the make up of the antigen. They then design a vaccine that raises the visibility of the antigen so that the immune system can identify it as a problem and eliminate the cancer/antigen cells. But this causes the PSA to rise, so until the stem cells have been given for a few weeks there will be few results that would not scare you. Dr. Moon said probably next week he will draw blood  and do a test to see where we are.
On another subject, lots of people are indicating their interest in the work being done over here. Dr. Moon has only so much space but is working an a new facility. When he first started this he did not think this would end up growing like this. He has purposely not advertised due to the lack of facilities and staff.
He is now working with the Mayo Clinic and the Grand Caymans to set up a facility in the US for testing and a facility in the Caymans for the treatments. This is because the vaccines and medicines are a combination of things that the FDA does not allow to be used in the states. The drug might be approved by the FDA in the states but it is not approved for this specific application.
He hopes to have the facilities up and running in the winter or spring of 2010.
The next question is can he help with a particular problem, cancer, Alzheimer, Parkinson, Hepitias C. etc. He can help in most cases but need to talk to the patient and do some blood work.
So contact me and I will give you the links and any  info I have. As you all know I'm no doctor so I can only tell of my experiences here and that of the other patients.This is my interpretation of things way over my head.
Mark

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Sunday 9/14
Not much to report today as we all got our standard treatments. We have had two new patients show up one from Oklahoma city the other from Florida up in the panhandle.
Our treatments or going to change tomorrow as the clinic is going to be sterilized for swine flew. So they are coming to the hotel and we are getting out treatments in our rooms. Pretty weird but cool.
One other thing we heard is  that there are 5 types of alzheimers 4 of which DR. Moon can stop and reverse and 1 he can only stop. But that gives me hope since I worry about myself some times. It has taken me a week to remember the names of the people here and I still have to think about it.
One of the new patients said that you can get the blood work of this caliber at UCLA but they cannot do any thing with it at this time. The question was asked if the blood test can tell if you are likely to have a problem in the future and the tests do show if the cells have the genes that will foster the growth of cancer etc. One of the patients that has been here 3 weeks came for Alzheimer and had the test and found out that he had the cells and a lesion on his lung that was going to go cancerous in time.
The other was the patient with the stage 4 lung cancer that was down to 20% they found that he had the extremely early stages of prostate cancer before it would show up on a psa test. So they are taking care of that to. I believe that I have mentioned this patient and how he came full fo cancer and it went down to 20% will the tests on friday  that the remaining 20% has broden up and is now just small pieces. so we will see.
Some of the family members are getting blood tests just to see if there is a future problem. It costs 2000.00 and forecasts out about 5 to 10 years but don't quote me on the time.
Thats it for now.
Mark and jack



Saturday sept 12,09  

*keep in mind, in the US we usually hear stem cell attahed to an argument involving babies...for you med techies here is blurb that seems to fit the definition they are using in S. Korea..what an education, right?? -kelly

Definition of Transplantation, peripheral blood stem cell

Transplantation, peripheral blood stem cell:A new technique in which stem cells are obtained from a patient's blood and used in bone marrow transplantation. Stem cells are small, round cells with a squat nucleus and scant surrounding cytoplasm. Although unremarkable in appearance, stem cells can perform what have been called "acts of biological resurrection." Whereas other types of cells in the body have a limited lifespan and die after dividing their endowed number of times, a stem cell can reproduce forever. The stem cell is immortal (in cellular terms).

A stem cell can forgo immortality and turn into an ordinary blood cell, a red blood cell (an erythrocyte), a white blood cell (a leukocyte), or a large cell (a megakaryocyte) that fragments into the platelets needed for blood to clot. A limited number of stem cells can miraculously repopulate the whole bone marrow, provide an endless supply of stem cells, reconstitute the entire repertory of blood cells, and restore the immune system.

To obtain the stem cells, the stem cells are lured out of the bone marrow by a special regimen of drugs. The blood is then filtered through a machine and the stem cells are skimmed off. The removal of the cells is termed pheresis or apheresis (from the Greek "aphairesis" for removal).

The stem cells then may be used right away for bone marrow transplant or stored in liquid nitrogen until needed. Before the transplant is done, the patient receives high-dose chemotherapy and/or radiation therapy to destroy diseased cells (the leukemic cells, lymphoma cells, solid tumor cells, the diseased immune system cells in scleroderma, etc.) The stem cells are then returned to the patient, where they can produce new blood and immune cells and replace the cells destroyed by the treatment. The stem-cell preparation is infused into a vein and, once there in the blood stream, the stem cells act like homing pigeons and head straight for the bone marrow space.

Back to Smith...
Here is the more accurate description of the process used in Korea. This is part of a longer letter that describes not only the process but the staffing requirement and so I cut out all but the description of the process.
Today the harvested Jackies blood and I got my first cell /vaccine and then we have Sunday off. so talk to you on Monday.
Mark and Jack
When a patient first arrives at the clinic, he/she will be given an injection which stimulates stem cell production. The patient will wait 36-48 hours for the stem cell production to increase. Around day 3 or 4 the patient will return to the clinic for the collection of stem cells/harvesting. This process involves a centrifuge machine connected to an I.V. set up. An I.V. catheter is inserted into the patients arm to draw blood. The blood is collected in the "Haemonetics" centrifuge machine. The machine separates the blood into separate sterile collection bags. One bag receives the plasma, a 2nd bag receives the red blood cells, and the 3rd bag receives the stem cells. The process of drawing blood takes eight minutes.
The machine then draws the plasma and red blood cells back into the centrifuge, spins the blood and replaces it, minus stem cells, back into the patient. This cycle continues every 8 minutes until 2 trillion stem cells are collected. The average time required for the complete process is 2-3 hours.
The stem cells are transferred to the lab. The lab analyzes the stem cells and develops a DNA vaccine which targets the specific markers and characteristics of the patient's unique cancer. The culture of the vaccine takes approximately 4 days.
The vaccine is injected into the stem cells. The stem cells act as a vehicle to transport the DNA vaccine to the cancer cells in the patients' body. The stem cell/vaccine is then administered to the patient by I.V. injection which normally takes about an hour. The patient is given the vaccine once per day for 8 days. Most patients require 2 full cycles of the vaccine, therefore, the stem cell collection process must also be performed twice, approximately 12 days apart.
The patient is also treated with an immune building gene therapy developed by Dr. Moon and his staff. The patients' blood is analyzed to determine his/her general health by looking for deficiencies in various amino acids, enzymes, hormones, proteins and other essential elements conducive to healing and immune support. An immune therapy "cocktail" is developed and administered by I.V. approximately every other day for the duration of the patients' stay. The immune therapy contains no FDA regulated medicines and falls into the category of "nutional supplement".


Hello everyone,
Today they harvested my white cells and will do Jackie tomorrow.  We are amazed at what other patients are going through. We just thought we would share some of our thoughts with everyone.
As most of you know we are having small things done daily, until we get the blood work back, but in the process we are still at the clinic everyday with everyone hearing what is going on with them and sharing our stories. There is one lady that everyone is very worried about. Her name is Crystal, she is here by herself and she is battling ovarian cancer. She is fairly young, but has been battling this for a while now. She has 2 boys at home with her husband, their ages are 10 and 13. she has been to Germany 3 or 4 times and  the treatments have not worked, so she is now here with us.  Jackie has gone to the hospital with her today to help her on the 1 hr drive to and from so we will get a report tonight.
Now more info on what is going on with the treatments.This is our interpretation and will have a more professional dialog tomorrow.
The cancer cells are caused due to a mis alignment [my way of describing it] of the DNA which caused the mutated cells to form. Dr. moon does extensive blood work to find out what is missing or wrong with the DNA patterns. At the same time he is also looking for other potential problems so they can be addressed at this time. He then designs a cocktail to fix this misalignment. From the harvested cells he manufactures more white cells and ,not real sure what else but should know tomorrow. So starting Monday they should start the daily IV of vitamins, white cells and the cocktail. So I believe that the theory is to stop the production of the cancer cells by realign the DNA and using the vitamins and new white cells to fight the old cancer cells. This is a construction workers take of the situation so who knows all I know is that one of the guys came here 4 weeks ago on oxygen with 80 percent of his lungs full of tumors and I saw the scans this morning and there is  now 1 tumor at about 20% with small floating tumors remaining. The only thing that is worrisome is if the blood work comes back with other problems. So we will see probably Monday.
Mark and Jack

 


Day 2

Hello everyone!
Not a lot to report, Jackie and I were both injected with white cell enhancer. Tomorrow I will be harvested for my white blood cells and then on Saturday Jackie will be harvested. We will not find out about any other problems until the blood work results come back. They are suppose to come in late this week, early next week latest. The blood work will determine how to procede from here and what treatments they will do to me.
Today we visited the Korean war Memorial with another couple and thier sons. We are learning to use the subway system here. It is pretty difficult not knowing the language, but we are getting through it. Luckily this other couple is walking us through it.
Will talk with everyone soon
Mark and Jackie

Day 1
Here we go on the adventure of medicine...
Well, we got off the plane at 6pm and did not have a driver to pick us up so we took a bus to the hotel. Next morning we went to breakfast and then met the other patients in the lobby and rode to the clinic on the shuttle. Lots of stories and good company. Dr moon met with us and said that I have a simple cancer that is only a single cancer and would not say that it was 100% guaranteed that it could be cured but said 90% sure.
the plan is to inject a white cell booster for 2 days, and then harvest white blood stem cells on the 3rd day. (they call the white blood cells, stem cells here, they are the fighter cells). Today they did an initial blood draw to determine type and amount cancer. This test will also determine any other types of cancers in the body. So they can fix those at the same time. They are also typing Jackie to see if she is a blood match, if she is they will also harvest her white blood stem cells to later inject into me. They will then begin manufacturing the white blood cells to be injected later. At this time they do not feel that Chemotherapy will be of any help, but we will not know until blood work is finished. The final determination will be a similar blood test they will perform during the process to see how it is all going. Final results are not based on PSA, but by the blood work to see if any cancer is still present.
One of the patients has been to Germany for treatment and feels extremely hopeful because this facility is far more technical. The clinic has a very hopeful feeling not like the US, where medicine is based on fear. The patients sit in a lobby type environment and we listen too and watch all that is going on with one another. It is very casual, extremely professional. The Korean culture/people are very caring and wonderful. So far we are still on track with thinking this is our solution!
Another one of the patients with lung cancer came in with stage 4 lung cancer and an oxygen tank and is now up and around without the oxygen tank. Dr, says that he is now about 80% clear. He has been here only 4-5 weeks and will only be here for another week. Wow!! The treatments appear to take no more than 3 hours a day, so we are getting the lay out of the city, how things work. We are located about 1 hour south of Seoul, so most of what we are seeing is still small city of Doksan, but still feels like a very large city to us. Everything is very different than we are used too. There are meat markets on the street corners and about 50 restaurants per block. Of which we have no idea what they serve. But again most of everyone we talk to speaks a little bit of English and is very accommodating.
The one downside that we have found is that the hotel is more expensive than we originally thought and food here is a bit pricey if you do not know what you are doing. Luckily there are names of restaurants that we all could recognize.
We will be in touch as we get more info. And we are very excited about everything.
Love,
Mark and Jackie